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NukleoPURE — five single-cell-selected nucleotides as cellular building blocks for healthy aging. If you want to live a longer, healthier life, start with the building blocks—not the symptoms. NukleoPURE provides defined, high-purity nucleotides in powder form: the building material your cells need for renewal, repair, and cellular relief. Pure, vegan, and free of additives—developed and manufactured in Switzerland.
Imagine your cells as a city. Every day, waste accumulates—metabolic byproducts, environmental pollutants, oxidative stress. And every day, new buildings (new cells) must be constructed. Longevity means keeping both in balance—as a longevity supplement, NukleoPURE focuses specifically on the second part.
Traditional detox products focus on "garbage collection": they are designed to help the body detoxify or cleanse cells from the inside. That's important—but it's only half the equation.
The other half: Your cells need fresh building blocks to continuously renew themselves. Your body produces 50 to 70 billion new cells every day. For each of these cells, your body needs 3.2 billion nucleotides—the basic building blocks of DNA and RNA.
As we age, the body’s production of new nucleotides decreases, and nucleotide metabolism and the availability of nucleotides in certain tissues may change—a connection that is gaining increasing scientific significance. At the same time, cellular stress is on the rise.
This is exactly where NukleoPURE comes in: It provides the specific building blocks your body needs for cellular renewal—in a formulation that has been scientifically proven to be ideal for your body—pure, highly bioavailable, and produced to Swiss laboratory standards.
Nucleotides are not just a passing fad. They are the most fundamental building blocks of life—and they are at the heart of every cellular renewal process. If you want to age healthily, you can’t ignore the cell. Nukleopure is designed for demanding applications and is unique due to its composition of individual nucleotides and its high nucleotide content.**
Dr. Peter Köppel Swiss biochemist and immunologist — over 30 years of nucleotide research and product development. Developer of the nucleotide combinations used in Vegana Natura
Both packages contain the same formula—you just choose how long you want to keep your cells nourished.
CHF 67.90
CHF 1.13 per day
The perfect way to get started—a full supply to help you incorporate NukleoPURE into your daily routine.
CHF 128.00CHF 135.80
CHF 1.07 per day
You'll save CHF 7.80For a consistent longevity routine—day after day, without interruption.
Nucleotides are the basic building blocks of DNA and RNA. They are the alphabet your body uses to write genetic information, build cells, and regenerate tissue.
Each of your more than 30 trillion cells carries your entire genetic information in the form of DNA. This DNA is made up of just four building blocks—nucleotides. Together with RNA, the cell’s “instruction manual,” nucleotides control how proteins are built, how cells divide, and how tissues regenerate.
Longevity research is increasingly focusing on cellular health—that is, the question of how well cells maintain their function over time. Nucleotides are not a “rejuvenation treatment” or an anti-aging miracle. However, they are the natural building blocks without which cell renewal, DNA repair, and cellular energy production cannot take place.
Endogenous production, recycling, and nutrition are sufficient as long as the demand is moderate. However, during periods of increased stress, after infections, or as we age, endogenous production can become labor-intensive and slow. That is precisely when NukleoPURE supplements the missing building blocks.
Each nucleotide performs a specific function in cellular structure. NukleoPURE combines all five—individually selected and in a highly pure form. The five nucleotides in NukleoPURE—AMP, CMP, GMP, IMP, and UMP—are precisely the building blocks that are recognized in European Food Regulation (EU) No. 609/2013 as a separate category of substances alongside vitamins, minerals, and amino acids.
Serves as a building block of RNA, as a precursor in energy metabolism, and as a signaling molecule. Provides the cell's energy currency.
Adenosine monophosphate
is a building block of RNA and a component of new cell membranes — essential for tissue regeneration.
Cytidine monophosphate
is a key building block for the formation of RNA, which is necessary for protein synthesis in cells.
Guanosine monophosphate
serves as a precursor for the formation of adenosine and guanosine nucleotides, which are important for cellular energy (ATP).
Inosine monophosphate
supports the regeneration of nerve fibers and the formation of cell membranes.
Uridine monophosphateDetoxification, autophagy, and gut restoration reduce the burden your cells have to cope with every day—metabolic waste products, environmental toxins, and oxidative stress are eliminated through the body’s excretory systems. This creates the foundation necessary for cellular repair to take place at all.
For every instance of cell renewal, the body needs nucleotides as the building blocks of DNA and RNA. A single cell division alone requires 3.2 billion nucleotides. Important: Nucleotides must be provided in a composition that is ideal for the body. NukleoPURE delivers five individually selected, high-purity nucleotides in a defined composition.
Cells divide, repair DNA, and replace worn-out tissue. Processes such as energy production and the immune system rely on rapid cell division. The more readily available the building blocks are, the more efficiently this process can take place—as a daily investment in your healthspan.
Detox clears the way. Nucleotides provide the building blocks. Only when the two work together do they create the longevity mechanism that takes effect at the cellular level. The first half—detoxification, gut restoration, and a healthy lifestyle—is up to you; NukleoPURE is designed for the second half of the equation.
Modern longevity research is no longer just about how we age, but about how long we remain vital and biologically young (healthspan rather than lifespan). In my complementary medicine practice, I see every day that chronic aging stress and the loss of vitality begin deep within the powerhouses of our cells—the mitochondria. When cellular energy production declines, degenerative processes accelerate throughout the entire body. That’s why I recommend nucleotides early on.**
Heinz Wattenhofer Complementary Medicine Therapist & Expert in Biological Cell Regeneration
Detoxification, autophagy, and gut restoration as the foundation: a system free of stress, in which cellular repair can actually take place. NukleoPURE provides the building blocks for the second half of the equation—CELL REGENERATION.
Five individually selected nucleotides as DNA/RNA building blocks—the material your body needs for natural cell renewal. Highly available and pure.
The Foundation for Healthy Aging—Longevity as a Daily Investment: It’s not just lifespan that counts, but the years you spend feeling vibrant and able to function—your healthspan.
1–2 g of powder daily — measure using the included measuring spoon or a precision scale.
Stir it into water, a smoothie, or a sports drink—and you're done. The powder is flavorless and versatile.
Longevity is a daily investment. Consistency matters more than quantity—make NukleoPURE a regular part of your routine.
Do not exceed the recommended daily dose of 2 g. Not suitable for people with gout, a yeast allergy, those who have undergone organ transplants, or those taking immunosuppressive medications. Consult a doctor before use if you are pregnant, breastfeeding, or taking medication.
“I use NukleoPURE in my practice as a supplement to detox treatments. The quality and transparency of the formulation are crucial to me as a therapist—and it’s very well-received by my clients. The fact that it’s made in Switzerland and is backed by Dr. Köppel’s research gives me the confidence I need.”
Heinz W. · Therapist Verified Purchase
"While searching for a reputable nucleotide product, I came across Vegana Natura—Swiss quality, transparently labeled, and free of marketing hype. It’s exactly what I’m looking for as a discerning user. The combination of a detox foundation and nucleotides fits perfectly with my approach to longevity."
Dr. Sandra H. Verified Purchase
“As I delved deeper into longevity and cellular health, it became clear: nucleotides are one of the cornerstones. NukleoPURE is the purest product I’ve found—no fillers, no additives, just the five building blocks. The powder form allows me to adjust the dose to my daily needs.”
Thomas B. Verified Purchase
FOCUS online and CHIP have published articles on nucleotides and longevity — read the articles.
The following scientific studies on nucleotides as dietary supplements are intended to provide scientific context and should be considered independently of this dietary supplement.
Schlosser P. et al. (2020). Genetic studies of urinary metabolites shed light on mechanisms of detoxification and excretion in humans. *Nature Genetics*, 52, 167–176 — identified 90 genes associated with metabolic, detoxification, and excretion processes.
Xu M, Liang R, et al. (2013). Dietary nucleotides extend the lifespan of Sprague-Dawley rats. J Nutr Health Aging, 17(3):223–9 — Animal study on the relationship between nucleotide intake and lifespan.
Zhu N, Liu X, Xu M, Li Y. (2021). Dietary Nucleotides Retard Oxidative Stress-Induced Senescence of Human Umbilical Vein Endothelial Cells. Nutrients, 13(9):3279 — on the effect of nucleotides on oxidative stress and cellular senescence.
Xu M, Liang R, Li Y, Wang J. (2017). Anti-fatigue effects of dietary nucleotides in mice. Food Nutr Res, 61(1):1334485 — on the effect of nucleotides on fatigue.
Carver JD. (1994). Dietary nucleotides: effects on the cellular immune system, the intestinal system, and the hepatic system. J Nutr, 124(1 Suppl):144S–148S — a classic review article on nucleotides and cellular systems.
Grimble GK. (1996). Why Are Dietary Nucleotides Essential Nutrients? Br J Nutr, 76(4):475–8 — discusses the conditions under which nucleotides can be considered essential.
Van Buren CT, Rudolph F. (1997). Dietary nucleotides: a conditional requirement. Nutrition, 13(5):470–2 — presents the need for nucleotides as conditional.
Gil A. (2002). Modulation of the immune response mediated by dietary nucleotides. Eur J Clin Nutr, 56 Suppl 3:S1–4 — Review article on the immunological significance of nucleotides.
Note: The studies listed examine nucleotides as a class of compounds in general, not NukleoPURE specifically. They do not constitute a claim regarding the efficacy of this product.
Nucleotides are the building blocks of DNA and RNA—the material essential for cell renewal, DNA repair, and tissue regeneration. Longevity, in the scientific sense, means keeping these cellular processes running efficiently over the long term. An adequate supply of nucleotides is essential for your body to maintain its repair and regeneration mechanisms.
Yes, nucleotides are essential for the formation of new cells. There are scientific studies—such as those on the senescence of endothelial cells under oxidative stress (Zhu et al. 2021)—that shed light on the connection between nucleotides and cellular senescence. We recommend reviewing the studies listed and consulting your doctor if you have specific questions.
For adults who want to specifically supplement their daily diet with nucleotides—particularly in the context of longevity, cellular health, and as a targeted longevity supplement. Also suitable for therapists and healthcare professionals.
Not suitable for people with gout, a yeast allergy, those who have undergone organ transplants, or those taking immunosuppressive medications. If you are pregnant, breastfeeding, or taking medication, consult your doctor before use.
Traditional detox products focus on elimination and detoxification—the “garbage collection” process. NukleoPURE complements this by providing the cellular building blocks the body needs for renewal. Detox clears the pathways; nucleotides supply the material. Only when the two work together do they create the longevity mechanism that operates at the cellular level.
As we age, nucleotide metabolism and the availability of nucleotides in certain tissues may change—a relationship that is currently being studied by scientists. At the same time, cellular stress can accumulate. NukleoPURE specifically supplements the daily diet with five individually selected nucleotides in a defined composition.
Yes. NukleoPURE can be easily combined with a detox or gut restoration program—in fact, that’s the recommended Longevity approach: first relieve the system, then provide the building blocks. It can also be combined with other Vegana-Natura products such as Immun & Cell, Colon & Cell, or probiotics. When combining with multiple supplements, the daily dose of 2 g of nucleotides should not be exceeded.
Longevity is not a quick fix, but a daily investment. Continuous use for at least 30–60 days is recommended to build up cellular reserves. Many users make NukleoPURE a regular part of their routine—the frequency is more important than the amount. There are no promises of healing or specific effects; it’s about providing the building blocks.
Give your body the building blocks it needs for cellular renewal—five carefully selected nucleotides, developed in Switzerland.
30-day money-back guarantee — no ifs, ands, or buts.
EU Health Claims Regulation (EC) No. 1924/2006: The health-related statements used on this page refer exclusively to the legally permitted structural/functional claims in accordance with the Health Claims Regulation (EC) No. 1924/2006. No disease-related statements are made, nor are any promises of healing or rejuvenation made.
Note on Nucleotides: The information on nucleotides explains their natural occurrence and their function as components of DNA and RNA. It is intended to provide a scientific context for biological processes and should be considered independently of this dietary supplement. It does not constitute a health claim or a description of the effects of NukleoPURE.
Note on Expert Quotes & Studies: Statements in the expert quote reflect the developer’s personal professional opinion. The scientific studies listed examine nucleotides as a class of compounds in general, not NukleoPURE specifically. They do not constitute a claim regarding the efficacy of this product.
Dietary Supplement Notice: Dietary supplements are not a substitute for a balanced, varied diet and a healthy lifestyle. Do not exceed the recommended daily intake. Keep out of reach of small children. Store in a cool, dry place. Not suitable for people with gout, yeast allergies, those who have undergone organ transplants, or those taking immunosuppressive medications. Consult a doctor before use if you are pregnant, breastfeeding, or taking medication.
